Enantiospecific total synthesis of pseudomonic acids from arabinose
โ Scribed by G.W.J. Fleet; M.J. Gough; T.K.M. Shing
- Publisher
- Elsevier Science
- Year
- 1983
- Tongue
- French
- Weight
- 188 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0040-4039
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๐ SIMILAR VOLUMES
Polyoxamic acid , 2-amino-2-deoxy-L-xylonic acid, is synthetized by thiophenoxide opening of a five-carbon chiral hydroxylated aziridine easily derived from L-arabinose. The formation of the carboxy group resulted lrom a Pummerer reaction. Polyoxins belong to a group of antifungal antibiotics produc
The R-and S-isomers of 8-and 12-hydroxyeicosatetraenoic acid (8-and lP-HETE) were synthesized from dimethyl malate derived precursors.
The synthesis of the cis-fused y-lactone 2,7-dioxabicycle-&3,4 non-4-en-g-one (3) by two routes is reported. Its stereoselective conversion to a key intermediate for pseudomonic acid synthesis is described.