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Enantiospecific Total Synthesis of (−)-( E )16-Epiaffinisine, (+)-( E )16-Epinormacusine B, and (+)-Dehydro-16-epiaffinisine as well as the Stereocontrolled Total Synthesis of Alkaloid G

✍ Scribed by Yu, Jianming; Wang, Tao; Wearing, Xiangyu Z.; Ma, Jun; Cook, James M.


Book ID
126998676
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
181 KB
Volume
68
Category
Article
ISSN
0022-3263

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The first enantiospecific total synthesi
✍ Jie Yang; Sundari K. Rallapalli; James M. Cook 📂 Article 📅 2010 🏛 Elsevier Science 🌐 French ⚖ 423 KB

The first enantiospecific total synthesis of the 3-oxygenated sarpagine indole alkaloids affinine (1) and 16-epiaffinine (2) as well as the synthesis of vobasinediol (3) and 16-epivobasinediol (4) was accomplished from D-(+)-tryptophan methyl ester.