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Enantiospecific synthesis of (R)-1,6-dioxaspiro[4.5]decane from a derivative of d-fructose

✍ Scribed by Isidoro Izquierdo Cubero; Maria T. Plaza López-Espinosa; Anthony C. Richardson; Kai H. Aamlid


Book ID
107727216
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
412 KB
Volume
242
Category
Article
ISSN
0008-6215

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Spiroketal equilibration: Interconversio
✍ Jae Uk Jeong; P.L. Fuchs 📂 Article 📅 1994 🏛 Elsevier Science 🌐 French ⚖ 279 KB

Acid-catalyzed equilibration of spiroketals 5SHp6 and 55Haj3 involves a two stage process whereby the 1,6-dioxaspiro]4.4]nonanes can be equilibrated under mild conditions to a pair of 1,6\_dioxaspiro[45]decanes with preservation of the adjacent C-20 methyl stereocenter. Under more forcing conditions