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Enantiospecific synthesis of optically pure (3s)-hydroxy esters by the stereocontrolled yeast reduction of α-sulfenyl-β-ketoesters

✍ Scribed by Tamotsu Fujisawa; Toshiyuki Itoh; Toshio Sato

Publisher: Elsevier Science
Year: 1984
Tongue: French
Weight: 291 KB
Volume: 25
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(01)91125-6

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✦ Synopsis

Stereocontrol in Baker's yedst reduction of B-ketoesters was sucoessfutly achieved by introducing the sulfenyl guu>up at cl-position of the esters to afford opticalZy pure íS)-& hydmxy esters.

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