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Enantiospecific synthesis of cyanocyclitols and (6R)-6-hydroxyshikimic acid from benzonitrile

✍ Scribed by Howard A.J. Carless; Yvonne Dove


Book ID
108036410
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
191 KB
Volume
7
Category
Article
ISSN
0957-4166

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## Abstract The enantioselective synthesis of [5‐^2^H]‐5‐epi‐shikimic acid starting from commercially available L‐shikimic acid has been accomplished in this work. The introduction of the stable isotope was facilitated by an enzymic reduction of a ketone. An interesting stereospecific enolisation w