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Enantioselectivity of the microsomal epoxide hydrolase-catalyzed hydrolysis of trans-4,5-dimethyl-1,2-epoxycyclohexane

โœ Scribed by Bellucci, Giuseppe; Berti, Giancarlo; Ferretti, Maria; Mastrorilli, Ettore; Silvestri, Luca


Book ID
126898369
Publisher
American Chemical Society
Year
1985
Tongue
English
Weight
550 KB
Volume
50
Category
Article
ISSN
0022-3263

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๐Ÿ“œ SIMILAR VOLUMES


Different enantioselectivity and regiose
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Abstractt The cytoaolic (cEH) mad the micmsonul cpoxidc bydtolasc (mEH) hydrolyac rtytenc oxide and tram-1-pbcnylproper oxide with different enmtio~elcctivity and ~~gioxelectivity. While mEEI always leads to l rcgiospccific and enxntio4&ive opening rt the non-bcnxylic oxinnc a&on. CEH given x aon-rc

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The microsomal epoxide hydrolase (mEH)-catalyzed hydrolysis of cis-4,4'-dimethylstilbene oxide (la), cis4,4'-diethylstilbene oxide (lb), cis-4,I'-diisopropylstilbene oxide (lc), and cis-4,4'-dichlorostilbene oxide (Id) have been investigated using rabbit liver microsomal preparations. The kinetic pa