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Enantioselectivity modulation through immobilization of Arthrobacter sp. lipase: Kinetic resolution of fluoxetine intermediate

✍ Scribed by Asha Chaubey; Rajinder Parshad; Surrinder Koul; Subhash C. Taneja; Ghulam N. Qazi


Book ID
113804093
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
179 KB
Volume
42
Category
Article
ISSN
1381-1177

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The lipase-catalyzed acetylation of a broad spectrum of configurations of the 2-hydroxy acids 1 were assigned by comparison of the gas-chromatographic data with that of racemic 2-hydroxy acids 1 to their 2-acetoxy acids 2 was shown to proceed with high enantioselectivity. Thus, the literature-known