Lipase-Catalyzed Enantioselective Synthesis of Methyl ( R )- and ( S )-2-Tetradecyloxiranecarboxylate through Sequential Kinetic Resolution
✍ Scribed by Jiménez, Oscar; Bosch, M. P.; Guerrero, Angel
- Book ID
- 127168566
- Publisher
- American Chemical Society
- Year
- 1997
- Tongue
- English
- Weight
- 172 KB
- Volume
- 62
- Category
- Article
- ISSN
- 0022-3263
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📜 SIMILAR VOLUMES
The lipase-catalyzed acetylation of a broad spectrum of configurations of the 2-hydroxy acids 1 were assigned by comparison of the gas-chromatographic data with that of racemic 2-hydroxy acids 1 to their 2-acetoxy acids 2 was shown to proceed with high enantioselectivity. Thus, the literature-known
## Abstract The enzyme‐catalyzed sequential esterification of (±)‐2‐methylpentanedioic anhydride (__rac__‐1) with 2‐methylpropanol in diethyl ether afforded a 1:1 mixture of 1‐(2‐methylpropyl) 5‐hydrogen (__S__)‐4‐methylpentanedioate (__ent__‐2) with an enantiomeric excess of 88% and 1‐(2‐methylpro
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