Trichloroethylene is a widespread industrial solvent and one of the most common environmental contaminants. Trichloroethylene causes hepatocarcinoma in the B6C3F 1 mouse in a dose-dependent manner. Trichloroethylene's hepatocarcinogenicity is thought to be mediated through its metabolites trichloroa
Enantioselectivity in the induction of peroxisome proliferation by 2-ethylhexanoic acid
✍ Scribed by Anne Christine Macherey; Stéphane Grégoire; Gérard Tainturier; Dr. Jean Claude Lhuguenot
- Publisher
- John Wiley and Sons
- Year
- 1992
- Tongue
- English
- Weight
- 600 KB
- Volume
- 4
- Category
- Article
- ISSN
- 0899-0042
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## Abstract Peroxisome proliferator‐activated receptor alpha (PPARα) is a member of the nuclear hormone receptor superfamily that can be activated by natural fatty acids and various xenobiotics, including clofibrate. This transcription factor primarily regulates genes involved in lipid metabolism a