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Enantioselective Total Synthesis of the Potent Anti-HIV Nucleoside EFdA

✍ Scribed by Kageyama, Masayuki; Nagasawa, Tomohiro; Yoshida, Mayumi; Ohrui, Hiroshi; Kuwahara, Shigefumi


Book ID
127016990
Publisher
American Chemical Society
Year
2011
Tongue
English
Weight
675 KB
Volume
13
Category
Article
ISSN
1523-7060

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✍ Jill Wilken; David Hoover; Darren A Thompson; Paul N Barlow; Helen McSparron; La πŸ“‚ Article πŸ“… 1999 πŸ› Elsevier Science 🌐 English βš– 1012 KB

## Background: Rantes is a cc-type chemokine protein that acts as a chemoattractant for several kinds of leukocytes, playing an important pro-inflammatory role. entry of human immunodeficiency virus-1 (hiv-1) into cells depends on the chemokine receptor ccr5. rantes binds ccr5 and inhibits hiv-1 en