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Enantioselective synthesis of β-amino esters bearing a quinazoline moiety via a Mannich-type reaction catalyzed by a cinchona alkaloid derivative

✍ Scribed by He, Ming; Pan, ZhaoXi; Bai, Song; Li, Pei; Zhang, YuPing; Jin, LinHong; Hu, DeYu; Yang, Song; Song, BaoAn


Book ID
119945680
Publisher
SP Science China Press
Year
2012
Tongue
English
Weight
562 KB
Volume
56
Category
Article
ISSN
1674-7291

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Enantioselective Synthesis of β-Amino Es
✍ Liang Li; Bao-An Song; Pinaki S. Bhadury; Yu-Ping Zhang; De-Yu Hu; Song Yang 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 424 KB 👁 1 views

## Abstract Novel β‐amino esters bearing a bioactive benzothiazole moiety were obtained with high enantioselectivities (up to 95 % __ee__) through a Mannich‐type reaction of different imines with malonate in the presence of a new chiral cinchona alkaloid thiourea catalyst. Imines derived from both