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Chiral cinchona alkaloid-derived thiourea catalyst for enantioselective synthesis of novel β-amino esters by mannich reaction

✍ Scribed by Weihua Li; Baoan Song; Pinaki S. Bhadury; Liang Li; Zhenchao Wang; Xiaoyan Zhang; Deyu Hu; Zhuo Chen; Yuping Zhang; Song Bai; Jian Wu; Song Yang


Book ID
112049427
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
910 KB
Volume
24
Category
Article
ISSN
0899-0042

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Enantioselective Synthesis of β-Amino Es
✍ Liang Li; Bao-An Song; Pinaki S. Bhadury; Yu-Ping Zhang; De-Yu Hu; Song Yang 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 424 KB 👁 1 views

## Abstract Novel β‐amino esters bearing a bioactive benzothiazole moiety were obtained with high enantioselectivities (up to 95 % __ee__) through a Mannich‐type reaction of different imines with malonate in the presence of a new chiral cinchona alkaloid thiourea catalyst. Imines derived from both