Highly Enantioselective Access to α-Dibe
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Pierre-Yves Géant; Jean Martínez; Xavier J. Salom-Roig
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Article
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2011
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John Wiley and Sons
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English
⚖ 491 KB
A novel and efficient synthesis of enantiomerically pure αdibenzylamino αЈ-sulfinyl ketones starting from a mixture of both epimers of α-bromo αЈ-(R)-sulfinyl ketone has been realized through combined in situ substitution-epimerization in a so-called Dynamic Kinetic Resolution (DKR). The scope of th