Der oft komplexe Zusammenhang von Spinund Ladungsverteilung lint sich an den Kontaktionenpadren des [15]Krone-5-2-aminonaphthosemichinon-Radikalanions 2 erliutern, welches wie die Titelverbindung I einen chinoiden Sechsring aufweist. Alkalimetall-Gegenkationen M" polarisieren infolge ihrer verschied
Enantioselective Synthesis of α-Amino Acetals and α-Amino Acids by Nucleophilic 1,2-Addition to Diethoxyacetaldehyde SAMP Hydrazone
✍ Scribed by Prof. Dr. Dieter Enders; Dr. Rudolf Funk; Dipl.-Chem. Martin Klatt; Dr. Gerhard Raabe; Dr. Eric R. Hovestreydt
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 536 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0044-8249
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📜 SIMILAR VOLUMES
The sequential addition of two different nucleophiles to a tartaric acid-derived nitrile produced carbinamines. The adducts from chelation-controlled addition which are obtained in high diastereoselectivities and yields, were easily converted to ct,ct-disubstituted-t~-amino acids.
The synthesis of tertiary carbinamines was achieved by the double nucleophilic addition of Grignard reagents to cyanohydrins. Titanium isopropoxide was found to promote the process. In a typical example, the rapid conversion of a carbinamine to the coresponding o~.o~-disubstitutedct-aminoacid was a