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Enantioselective Synthesis of the Metabolites of Vasopressin V2 Receptor Antagonist OPC-31260 via Lipase-Catalyzed Transesterification

✍ Scribed by Jun Matsubara; Kazuyoshi Kitano; Kenji Otsubo; Yoshikazu Kawano; Tadaaki Ohtani; Masahiko Bando; Masaru Kido; Minoru Uchida; Fujio Tabusa

Book ID
108370854
Publisher
Elsevier Science
Year
2000
Tongue
French
Weight
296 KB
Volume
56
Category
Article
ISSN
0040-4020

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πŸ“œ SIMILAR VOLUMES

ChemInform Abstract: Enantioselective Sy
ChemInform Abstract: Enantioselective Synthesis of the Metabolites of Vasopressin V2 Receptor Antagonist OPC-31260 via Lipase-Catalyzed Transesterification.
✍ Jun Matsubara; Kazuyoshi Kitano; Kenji Otsubo; Yoshikazu Kawano; Tadaaki Ohtani; πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons βš– 43 KB πŸ‘ 2 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a β€œFull Text” option. The original article is trackable v

An efficient synthesis of optically acti
An efficient synthesis of optically active metabolites of platelet adhesion inhibitor OPC-29030 by lipase-catalyzed enantioselective transesterification
✍ Kazuyoshi Kitano; Jun Matsubara; Tadaaki Ohtani; Kenji Otsubo; Yoshikazu Kawano; πŸ“‚ Article πŸ“… 1999 πŸ› Elsevier Science 🌐 French βš– 245 KB

Aletraa:. The optically active metabolites of (S)-3,4-dihydro-6-[3-(1-o-tolyl-2-imidazolyl)sulfmylpropoxy]-2(I/-/)-qninolinone (OPC-29030, 1), which is a new anti-platelet agent (platelet adhesion inhibitor), were effectively synthesized by the enzyme-catalyzed enantinselective transesterificatinn o