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Enantioselective synthesis of the individual stereoisomers of a brassinolide mimetic

โœ Scribed by Thomas G. Back; Michael A. Bey; Masood Parvez; Richard P. Pharis


Book ID
108283735
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
344 KB
Volume
15
Category
Article
ISSN
0957-4166

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๐Ÿ“œ SIMILAR VOLUMES


A concise synthesis of the brassinolide
โœ Thomas G. Back; Peter G. Blazecka; M. Vijaya Krishna ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 82 KB

The brassinolide side chain was produced by the addition of (E)-propenyllithium to the C-22 aldehyde 2, followed by Sharpless epoxidation and epoxide opening with i-Pr2CuCNLi 2. Brassinolide 1(!) is a potent plant growth-promoter that was discovered by Grove et al. in 1979. 2 Its biological activit