Enantioselective Synthesis of the Diazatricyclic Core of Alkaloid TAN1251C via an Iodoaminocyclization Reaction
β Scribed by Hongkui Zhang; Zhijie Lin; Huang Huang; Haohua Huo; Yanju Huang; Jianliang Ye; Peiqiang Huang
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 149 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0256-7660
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An Enantioselective Synthesis of Natural (-)-Huperzine A via Cinchona Alkaloid Promoted Asymmetric Michael Reaction. -An improved synthesis of the title compound is developed via the known intermediate (+)-(III) derived from the Ξ²-keto ester (I). After one recrystallization (+)-(III) is obtainable
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