𝔖 Bobbio Scriptorium
✦   LIBER   ✦

ChemInform Abstract: An Enantioselective Synthesis of Natural (-)-Huperzine A via Cinchona Alkaloid Promoted Asymmetric Michael Reaction.

✍ Scribed by S. KANEKO; T. YOSHINO; T. KATOH; S. TERASHIMA

Publisher
John Wiley and Sons
Year
2010
Weight
31 KB
Volume
29
Category
Article
ISSN
0931-7597

No coin nor oath required. For personal study only.

✦ Synopsis

An Enantioselective Synthesis of Natural (-)-Huperzine A via Cinchona Alkaloid Promoted Asymmetric Michael Reaction.

-An improved synthesis of the title compound is developed via the known intermediate (+)-(III) derived from the Ξ²-keto ester (I). After one recrystallization (+)-(III) is obtainable with 99% e.e. The synthesis of the enantiomer (-)-(III) is also possible by this method using (+)-cinchonine.

-(KANEKO, S.;

πŸ“œ SIMILAR VOLUMES

ChemInform Abstract: Enantioselective Sy
ChemInform Abstract: Enantioselective Synthesis of Phosphinyl Peptidomimetics via an Asymmetric Michael Reaction of Phosphinic Acids with Acrylate Derivatives.
✍ Xuewei Liu; X. Eric Hu; Xinrong Tian; Adam Mazur; Frank H. Ebetino πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 29 KB πŸ‘ 1 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a β€œFull Text” option. The original article is trackable v