ChemInform Abstract: An Enantio- and Stereocontrolled Synthesis of (-)-Mycestericin E via Cinchona Alkaloid Catalyzed Asymmetric Baylis—Hillman Reaction.
✍ Scribed by Yoshiharu Iwabuchi; Mariko Furukawa; Tomoyuki Esumi; Susumi Hatakeyama
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 32 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0931-7597
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An Enantioselective Synthesis of Natural (-)-Huperzine A via Cinchona Alkaloid Promoted Asymmetric Michael Reaction. -An improved synthesis of the title compound is developed via the known intermediate (+)-(III) derived from the β-keto ester (I). After one recrystallization (+)-(III) is obtainable
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