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Enantioselective synthesis of (R)-(+)-β-piperonyl-γ-butyrolactone

✍ Scribed by Hiram C.A. Filho; Ubiracir F.L. Filho; Sergio Pinheiro; Mario L.A.A. Vasconcellos; Paulo R.R. Costa

Book ID: 103977053
Publisher: Elsevier Science
Year: 1994
Tongue: English
Weight: 132 KB
Volume: 5
Category: Article
ISSN: 0957-4166
DOI: 10.1016/0957-4166(94)80161-4

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✦ Synopsis

Lactone (RX+)-1, was prepared from (2S)-(-)-2-allyl-[3',4'-(methylenedioxy)phenyl] propan-l-01 (7). This intermediate was synthesized by two complemenw pathways, using as the key steps the diastereoselective alkylation of esters 4 and 5, respectively.

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