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Enantioselective synthesis of (R)-(−)-laudanosine and (R)-(−)-glaucine from L-ascorbic acid

✍ Scribed by Zbigniew Czarnocki; Józef B. Mieczkowski; Marek Ziólkowski


Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
543 KB
Volume
7
Category
Article
ISSN
0957-4166

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📜 SIMILAR VOLUMES


Enantioselective Synthesis of (R)-(+)-Pu
✍ Rödel, Thomas ;Gerlach, Hans 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 451 KB

## Abstract The fungal metabolite (__R__)‐(+)‐pulvilloric acid [(+)‐1] was synthesized for the first time. Reaction of the Grignard reagent of 5 with 2‐pentyloxirane (__S__)‐(−)‐4 in the presence of 1,5‐cyclooctadienecopper(I) chloride as the catalyst led to (__S__)‐(+)‐6. The enantiomer (__S__)‐(−