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Enantioselective synthesis of quaternary carbon centers through Michael-type alkylation of chiral imines

✍ Scribed by Pfau, Michel; Revial, Gilbert; Guingant, Andre; d'Angelo, Jean


Book ID
126176410
Publisher
American Chemical Society
Year
1985
Tongue
English
Weight
286 KB
Volume
107
Category
Article
ISSN
0002-7863

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Enantioselective synthesis of ring-C aro
✍ Tony Volpe; Gilbert Revial; Michel Pfau; Jean d'Angelo πŸ“‚ Article πŸ“… 1987 πŸ› Elsevier Science 🌐 French βš– 219 KB

Optically active phenanthrones 7 and 12 were prepared, using the asymmetric process involving Michael-type alkylation of chiral imines. Compound 12 was then transformed into the ring-C aromatic steroid 16. We have recently published a very efficient method for the enantioselective construction of co