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Enantioselective Synthesis of Indoloquinolizidines via Asymmetric Catalytic Hydrogenation/Lactamization of Imino Diesters

✍ Scribed by Liu, Yong; Wang, Qun; Zhang, Ying; Huang, Jianbiao; Nie, Linlin; Chen, Jie; Cao, Weiguo; Wu, Xiaoyu


Book ID
121397046
Publisher
American Chemical Society
Year
2013
Tongue
English
Weight
486 KB
Volume
78
Category
Article
ISSN
0022-3263

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Catalytic enantioselective synthesis of
✍ Graham B. Jones; Robert S. Huber; Brant J. Chapman πŸ“‚ Article πŸ“… 1997 πŸ› Elsevier Science 🌐 English βš– 874 KB

Catalytic enantioselective syntheses of the macrolides (R)-(-) phoracantholide and (R)-(+) lasiodiplodin have been achieved. Stereochemistry was introduced in using an arene chromium tricarbonyl derived catalyst, which mediated the enantioselective addition of dimethyl zinc to a functionalized aldeh