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Enantioselective Synthesis of Bridgehead Hydroxyl Bicyclo[2.2.2]octane Derivatives via Asymmetric Allylindation.

โœ Scribed by Viveca Thornqvist; Sophie Manner; Torbjoern Frejd


Publisher
John Wiley and Sons
Year
2006
Weight
21 KB
Volume
37
Category
Article
ISSN
0931-7597

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## Abstract The synthesis of the enantiomerically pure, bridgeheadโ€functionalized bicyclo[3.2.1]octanes 11 and 16, containing a conformationally fixed trihydroxypropyl (aminodihydroxypropyl) unit, as well as the Xโ€ray structure of 11 are described. These compounds are of interest as sugar surrogate