Enantioselective synthesis of both (+)- and (−)-derivatives of bicyclo[4.3.0]nonan-8-one and -3,8-diones from R-carvone
✍ Scribed by Adusumilli Srikrishna; T.Jagadeeswar Reddy; Sankuratri Nagaraju
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- French
- Weight
- 242 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Alkylation of bicyclo[3.3.0]octane‐2,8‐dione (**1**), which is prepared by a modification of the procedure described in the literature, gives the methyl‐ and propynyl‐derivatives **6** and **7** (__Scheme 1__). In addition to the method described previously (__Scheme 2__), 9‐methyl‐__ci
1,2 Disubstituted methylenecyclopropyl bromides, 6 and 11, undergo radical cascade reactions, involving cyclisation, ring-opening and further cyclisation, to give cis bicyclic products in 67% and 41% yields respectively.