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Enantioselective synthesis of bicylco[3.2.1]octan-8-ones using a tandem Michael–Henry reaction

✍ Scribed by Derong Ding; Cong-Gui Zhao; Qunsheng Guo; Hadi Arman


Book ID
108283295
Publisher
Elsevier Science
Year
2010
Tongue
French
Weight
300 KB
Volume
66
Category
Article
ISSN
0040-4020

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## Abstract An enantioselective oxa‐Michael–Henry reaction of substituted salicylaldehydes with nitroolefins that proceeds though an aromatic iminium activation (AIA) has been developed by using a chiral secondary amine organocatalyst and salicylic acid as a co‐catalyst. The corresponding 3‐nitro‐2