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Enantioselective Synthesis of Arglabin

✍ Scribed by Srinivas Kalidindi; Won Boo Jeong; Andreas Schall; Rakeshwar Bandichhor; Bernd Nosse; Oliver Reiser


Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
160 KB
Volume
46
Category
Article
ISSN
0044-8249

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An enantioselective synthesis of cordiachromene is described. An allylic alcohol moiety is first attached in the oposition to the methoxymethoxy substituent in 1-methoxy-4methoxymethoxybenzene. Then chirality is introduced successively through asymmetric Sharpless epoxidation on the allylic alcohol