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Enantioselective synthesis of (+)- and (−)-dihydrokawain

✍ Scribed by Claude Spino; Nigel Mayes; Hélène Desfossés; Subramaniam Sotheeswaran


Book ID
103414250
Publisher
Elsevier Science
Year
1996
Tongue
French
Weight
213 KB
Volume
37
Category
Article
ISSN
0040-4039

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An enantioselective synthesis of cordiachromene is described. An allylic alcohol moiety is first attached in the oposition to the methoxymethoxy substituent in 1-methoxy-4methoxymethoxybenzene. Then chirality is introduced successively through asymmetric Sharpless epoxidation on the allylic alcohol