Enantioselective synthesis of hematoporp
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Dirk Kusch; Franz-Peter Montforts
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Article
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1995
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Elsevier Science
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English
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The reduction of 3,8-diacetyl porphyrin I with borane-methyl sulfide complex, BMS, as stoichiometric reductant and rnethyloxazaborolidine 2 and ent-2 as catalysts allows the enantioselective preparation of hematoporphyrin IX dimethyl ester stereoisomers. Hematoporphyrin was first obtained by THUDIC