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Enantioselective syntheses and calcium channel modulating effects of (+)- and (−)-3-isopropyl 5-(4-methylphenethyl) 1,4-dihydro-2,6-dimethyl-4-(2-pyridyl)-3,5-pyridinedicarboxylates

✍ Scribed by Nadeem Iqbal; Dean Vo; Carol-Anne McEwen; Michael W. Wolowyk; Dr. Edward E. Knaus


Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
550 KB
Volume
6
Category
Article
ISSN
0899-0042

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ChemInform Abstract: Synthesis and Calci
✍ R. MIRI; S. E. HOWLETT; E. E. KNAUS 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 31 KB 👁 2 views

Synthesis and Calcium Channel Modulating Effects of Isopropyl 1,4-Dihydro-2,6-dimethyl-3-nitro-4-(thienyl)-5-pyridinecarboxylates. -The synthesis of the title compounds (IV) (6 examples) by a modified Hantzsch reaction is reported. All the compounds exhibited only weak calcium channel antagonist act