𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Enantioselective separations of chiral molecules by μ-HPLC and SFC on microbore and packed microcapillary columns

✍ Scribed by D'Acquarica, Ilaria ;Gasparrini, Francesco ;Giannoli, Barbara ;Misiti, Domenico ;Villani, Claudio ;Mapelli, Gian Pietro

Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
274 KB
Volume
20
Category
Article
ISSN
0935-6304

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

New results obtained with microbore or microcapillary columns packed with DACH‐DNB CSP (spherical silica, 5 μm) using conventional LC eluents or supercritical fluids are reported. Examples of direct chromatographic separations of complex mixtures of stereo‐isomers on: a) long, packed microbore or microcapillary columns and b) several columns coupled in series are shown; in the latter case, a home‐made calculation procedure (Simulation for Multi‐Column Chromatography–SMCC) was used to quickly select the optimal conditions (kind of stationary phases and relative columns length).

📜 SIMILAR VOLUMES

Chiral separation of 1,1′-bi-2-naphthol
Chiral separation of 1,1′-bi-2-naphthol and its analogue on molecular imprinting monolithic columns by HPLC
✍ Junjie Ou; Shouwan Tang; Hanfa Zou 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 483 KB

## Abstract Two molecular imprinting polymer (MIP) monolithic columns with (__S__)‐(–)‐1,1′‐bi‐2‐naphthol and (__R__)‐(+)‐5,5′,6,6′,7,7′,8,8′‐octahydro‐1,1′‐bi‐2‐naphthol as the templating molecules, respectively, have been prepared by __in situ__ polymerization using 4‐vinylpyridine and ethylene d

Direct enantioselective separation of so
Direct enantioselective separation of some propranolol analogs by HPLC on normal and reversed cellulose chiral stationary phases
✍ Hassan Y. Aboul-Enein; Laila I. Abou-Basha; Soliman A. Bakr 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 374 KB 👁 2 views

The enantiomeric separation of several racemic aryloxyaminopropan-2-01 derivatives related to propranolol on normal and reversed phase of cellulose tris (3,5-dimethylphenyl carbamate) chiral stationary phases known as Chiralcel OD and Chiralcel OD-R were studied. It was observed that the chiral sepa