Enantioselective separation and determination of adrafinil and modafinil on Chiralcel OJ-H column in rat serum and urine using solid-phase extraction followed by HPLC

Determination of antihyperglycemic bigua

Determination of antihyperglycemic biguanides in serum and urine using an ion-pair solid-phase extraction technique followed by HPLC-UV on a pentafluorophenylpropyl column and on an octadecyl column

✍ Kayoko Tahara; Ayumi Yonemoto; Yuji Yoshiyama; Toshiya Nakamura; Masaaki Aizawa; 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 195 KB 👁 1 views

An HPLC-UV method was established for the determination of metformin and buformin in biological fluids. Metformin was not retained on particles packed in conventional solid-phase extraction cartridges; in contrast, buformin was retained too firmly and not eluted with a solvent for recovery. However,