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Enantioselective reduction of aryl trifluoromethyl ketones with BINAL-H. A preparation of 2,2,2-trifluoro-1-(9-anthryl)ethanol

โœ Scribed by Chong, J. Michael; Mar, Eduardo K.


Book ID
115548809
Publisher
American Chemical Society
Year
1991
Tongue
English
Weight
586 KB
Volume
56
Category
Article
ISSN
0022-3263

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Preparation of 1-(9-anthryl)-ethanol and
โœ I. Reiners; J. Martens ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 120 KB

Enantioselective reduction of prochiral 9-anthryl ketones to the corresponding chiral alcohols proceeds with high enantiomeric excess. The chiral alcohol 1-(9-anthryl)-2-bromo-ethanol can be converted to the corresponding chiral oxirane. (~