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Enantioselective Oxidation of trans -4-Hydroxy-2-Nonenal Is Aldehyde Dehydrogenase Isozyme and Mg 2+ Dependent

✍ Scribed by Brichac, Jiri; Ho, Kwok Ki; Honzatko, Ales; Wang, Rongying; Lu, Xiaoning; Weiner, Henry; Picklo, Matthew J.


Book ID
126112103
Publisher
American Chemical Society
Year
2007
Tongue
English
Weight
376 KB
Volume
20
Category
Article
ISSN
0893-228X

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The hepatic oxidation of ethanol has been demonstrated to cause peroxidation of cellular membranes, resulting in the production of aldehydes that are substrates for hepatic aldehyde dehydrogenases. It was the purpose of this study to evaluate the cooxidation of the lipid peroxidation product, truns-