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Enantioselective Organocatalytic Tandem Michael—Aldol Reactions: One-Pot Synthesis of Chiral Thiochromenes.

✍ Scribed by Wei Wang; Hao Li; Jian Wang; Liansuo Zu

Publisher
John Wiley and Sons
Year
2006
Weight
29 KB
Volume
37
Category
Article
ISSN
0931-7597

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A Highly Enantioselective Catalytic Domino Aza-Michael/Aldol Reaction: One-Pot Organocatalytic Asymmetric Synthesis of 1,2-Dihydroquinolidines
✍ Henrik Sundén; Ramon Rios; Ismail Ibrahem; Gui-Ling Zhao; Lars Eriksson; Armando 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 188 KB 👁 2 views

## Abstract The highly enantioselective organocatalytic domino aza‐Michael/aldol reaction is presented. The unprecedented, chiral amine‐catalyzed asymmetric domino reactions between 2‐aminobenzaldehydes and α,β‐unsaturated aldehydes proceed with excellent chemo‐ and enantioselectivity to give the c