Enantioselective Organocatalytic Rearrangement of α-Acyloxy- β-keto Sulfides to α-Acyloxy Thioesters
✍ Scribed by Francesca Capitta; Angelo Frongia; Pier Paolo Piras; Patrizia Pitzanti; Francesco Secci
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 204 KB
- Volume
- 352
- Category
- Article
- ISSN
- 1615-4150
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## Abstract The enantioselective hydrogenation of β‐(acyloxy)‐ and β‐(acylamino)vinylphosphonates with rhodium catalysts based on chiral phosphane‐phosphite ligands has been studied. In the case of the β‐(acyloxy)vinylphosphonates, the reaction also produces an achiral phosphonate resulting from th
## Abstract The Rh complex (RPO) efficiently promotes the asymmetric hydrogenation of title phosphonates giving synthetically and biologically important β‐functionalized phosphonates in high optical purity.