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Enantioselective Organocatalytic Cascade Reactions

✍ Scribed by Magnus Rueping

Publisher
John Wiley and Sons
Year
2007
Weight
11 KB
Volume
38
Category
Article
ISSN
0931-7597

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Highly Enantioselective Organocatalytic Cascade Reaction for the Synthesis of Piperidines and Oxazolidines. -Organocatalyzed Michael addition of amidomalonates, e.g. (I) and (VI), towards enals (II) followed by intramolecular hemiaminal formation provides enantioenriched piperidine derivatives (III)