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Enantioselective Organocatalytic Allylic Amination.

✍ Scribed by Thomas B. Poulsen; Carlos Alemparte; Karl Anker Joergensen


Book ID
101981748
Publisher
John Wiley and Sons
Year
2005
Weight
40 KB
Volume
36
Category
Article
ISSN
0931-7597

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Organocatalytic α-amination–allylation-R
✍ Aram Lim; Jung Hoon Choi; Jinsung Tae 📂 Article 📅 2008 🏛 Elsevier Science 🌐 French ⚖ 193 KB

A highly enantioselective method for the synthesis of cyclic hydrazines by using organocatalytic a-amination-allylation-RCM strategy is described. Proline-catalyzed a-amination of aldehydes followed by indium-mediated one-pot allylation of the crude a-hydrazino aldehydes produces 1,2-aminoalcohols i