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Enantioselective HPLC analysis of propafenone and of its main metabolites using polysaccharide and protein-based chiral stationary phases

โœ Scribed by Pierina Sueli Bonato; Luis Renato Pires de Abreu; Cristiane Masetto de Gaitani; Vera Lucia Lanchote; Carlo Bertucci


Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
67 KB
Volume
14
Category
Article
ISSN
0269-3879

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## Abstract A quick and sensitive reversedโ€phase HPLC method has been developed for the analysis of 2โ€ฒโ€ฮฒ โ€fluoroโ€2โ€ฒ,3โ€ฒโ€dideoxy adenosine (Fโ€ddA), the acidโ€stable antiโ€AIDS drug, and its metabolite 2โ€ฒโ€fluoroโ€2โ€ฒ,3โ€ฒโ€dideoxy inosine (Fโ€ddI) in human plasma using polyfluorinated stationary phase column