Three fungicidal triazolyl alcohols (triadimenol, hexaconazole, and cis/ trans-1-4-chlorophenyl-2-1H-1,2,4-triazol-1-yl-cycloheptanol) were completely separated into enantiomers by chiral HPLC using polysaccharide-based chiral stationary phases. A better separation was achieved on cellulose and amyl
Enantioselective HPLC analysis of propafenone and of its main metabolites using polysaccharide and protein-based chiral stationary phases
โ Scribed by Pierina Sueli Bonato; Luis Renato Pires de Abreu; Cristiane Masetto de Gaitani; Vera Lucia Lanchote; Carlo Bertucci
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 67 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0269-3879
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๐ SIMILAR VOLUMES
Chiral stationary phases (CSPs) are becoming abundant and extensively used in resolution of drug racemates. The polysaccharide-type CSPs namely the cellulose and amylose derivatives are widely used in the resolution and analysis of racemate drugs by high performance liquid chromagraphy (
## Abstract A quick and sensitive reversedโphase HPLC method has been developed for the analysis of 2โฒโฮฒ โfluoroโ2โฒ,3โฒโdideoxy adenosine (FโddA), the acidโstable antiโAIDS drug, and its metabolite 2โฒโfluoroโ2โฒ,3โฒโdideoxy inosine (FโddI) in human plasma using polyfluorinated stationary phase column