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Enantioselective Enzymatic Aminolysis and Ammonolysis of Dimethyl 3-Hydroxyglutarate. Synthesis of ( R )-4-Amino-3-hydroxybutanoic Acid

✍ Scribed by Puertas, Susana; Rebolledo, Francisca; Gotor, Vicente


Book ID
126301048
Publisher
American Chemical Society
Year
1996
Tongue
English
Weight
159 KB
Volume
61
Category
Article
ISSN
0022-3263

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✍ Monica G. Fritz; Dieter Seebach πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 German βš– 228 KB πŸ‘ 2 views

The benzyl esters 1 Β± 3 of oligo[(R)-3-hydroxybutanoic acids] (OHB) containing 2, 16, or 32 HB units were coupled at the hydroxy terminus with arginine (by esterification with carbodiimide), with glucose (by acetalization with glucosyl trichloroacetimidate), and with 7-(dimethylamino)coumarin-4-acet