## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
Enantioselective diethylzinc addition to aldehydes using azetidine-derived chiral catalysts
β Scribed by P.J Hermsen; J.G.O Cremers; L Thijs; B Zwanenburg
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- French
- Weight
- 56 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0040-4039
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β¦ Synopsis
High levels of enantioselectivity have been achieved in the diethylzinc addition to both aromatic and aliphatic aldehydes, employing readily available N-substituted-azetidinyl(diphenylmethyl)methanols as chiral catalysts.
π SIMILAR VOLUMES
The enantioselective additionof diethylxinc to ztldehydes using 1,2-isopropylidene-Sdeoxy-5-dialkylammO-U-D-XylOfuranOse8 derived from a-D-xylose as new catalysts provided the corresponding alcohlos with 75-96 % ee. Enantioselective addition of diethylzinc to aldehydes by chiral ligands is a conven
Optically active amino thioacetate derivatives of (+l-norephedrine were found to act as effective catalysts for enantioselective addition of diethylzinc to aldehydes. This reaction provided optically active secondary alcohols with e.e. of up to >99%.
## Abstract The new chiral Ξ²βaminoalcohols of indolinylmethanols (__1__) and their reduced derivatives (__2__) were synthesized from (__S__)βindolineβ2βcarboxylic acid. Both (__R__) and (__S__) enantiomers of the optically active secondary alcohols have been successfully obtained in high enantiomer