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Enantioselective diethylzinc addition to aldehydes using azetidine-derived chiral catalysts

✍ Scribed by P.J Hermsen; J.G.O Cremers; L Thijs; B Zwanenburg


Publisher
Elsevier Science
Year
2001
Tongue
French
Weight
56 KB
Volume
42
Category
Article
ISSN
0040-4039

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✦ Synopsis


High levels of enantioselectivity have been achieved in the diethylzinc addition to both aromatic and aliphatic aldehydes, employing readily available N-substituted-azetidinyl(diphenylmethyl)methanols as chiral catalysts.


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