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Enantioselective Cyanosilylation of Ketones Catalyzed by Double-Activation Catalysts with N-Oxides.

โœ Scribed by Fu-Xue Chen; Bo Qin; Xiaoming Feng; Guolin Zhang; Yaozhong Jiang


Publisher
John Wiley and Sons
Year
2005
Weight
39 KB
Volume
36
Category
Article
ISSN
0931-7597

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Enantioselective Cyanosilylation of Keto
โœ Fu-Xue Chen; Hui Zhou; Xiaohua Liu; Bo Qin; Xiaoming Feng; Guolin Zhang; Yaozhon ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 223 KB ๐Ÿ‘ 2 views

## Abstract Doubleโ€activation catalysis promises high catalytic efficiency in the enantioselective cyanosilylation of ketones through the combined use of a Lewis acid and a Lewis base. Catalyst systems composed of a chiral salenโ€“Al complex and an Nโ€oxide have high catalytic turnovers (200 for aroma

Enantioselective Cyanosilylation of Keto
โœ Yan Xiong; Xiao Huang; Shaohua Gou; Jinglun Huang; Yuehong Wen; Xiaoming Feng ๐Ÿ“‚ Article ๐Ÿ“… 2006 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 138 KB ๐Ÿ‘ 2 views

## Abstract An efficient and optically active, bifunctional tetraaza ligand (2__S__)โ€__N__โ€{(1__R__,2__R__)โ€2โ€[(__S__)โ€pyrrolidineโ€2โ€carboxamido]โ€1,2โ€diphenylethyl}pyrrolidineโ€2โ€carboxamide has been developed for the addition of trimethylsilyl cyanide (TMSCN) to ketones. The bifunctional catalyst s