Enantioselective Cyanosilylation of Ketones Catalyzed by Double-Activation Catalysts with N-Oxides.
โ Scribed by Fu-Xue Chen; Bo Qin; Xiaoming Feng; Guolin Zhang; Yaozhong Jiang
- Publisher
- John Wiley and Sons
- Year
- 2005
- Weight
- 39 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0931-7597
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๐ SIMILAR VOLUMES
## Abstract Doubleโactivation catalysis promises high catalytic efficiency in the enantioselective cyanosilylation of ketones through the combined use of a Lewis acid and a Lewis base. Catalyst systems composed of a chiral salenโAl complex and an Nโoxide have high catalytic turnovers (200 for aroma
## Abstract An efficient and optically active, bifunctional tetraaza ligand (2__S__)โ__N__โ{(1__R__,2__R__)โ2โ[(__S__)โpyrrolidineโ2โcarboxamido]โ1,2โdiphenylethyl}pyrrolidineโ2โcarboxamide has been developed for the addition of trimethylsilyl cyanide (TMSCN) to ketones. The bifunctional catalyst s