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Enantioselective addition of EtzZn to aldehydes catalyzed by chiral aliphatic β-amino alcohols

✍ Scribed by Shen Zong-Xuan; Xu Xue-Nong; Liu Xiao-Feng; Zhang Li-Fen; Zhang Ya-Wen


Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
205 KB
Volume
18
Category
Article
ISSN
0256-7660

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Enantioselective Addition of Phenylacety
✍ Juan Ding; Zong-Xuan Shen; Xiao-Qing Luo; Wei-Yi Chen; Ya-Wen Zhang 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 69 KB 👁 2 views

## Abstract (__S__)‐(1‐Benzylpyrrolidin‐2‐yl)diphenylmethanol and cinchonine were evaluated as promotors in the asymmetric additions of phenylacetylene to ketones, in order to prepare chiral propargylic alcohols. Good yields (up to 89%) and moderate enantioselectivities (up to 77.9% __ee__) were ac