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Enantioselective [2,3]Wittig rearrangement involving a chiral boron enolate terminus

✍ Scribed by Katsuhiko Fujimoto; Takeshi Nakai


Book ID
104214528
Publisher
Elsevier Science
Year
1994
Tongue
French
Weight
321 KB
Volume
35
Category
Article
ISSN
0040-4039

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πŸ“œ SIMILAR VOLUMES


External chiral ligand-induced enantiose
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The external chiral ligand-induced enantioselective [2,3]-Wittig rearrangements of crotyl benzyl ethers and crotyl propargylic ethers are described. The most notable is that treatment of (E)-crotyl propargylic ethers with a t-butyllithium/(S;S)-bis(oxazoline) complex provides a relatively high enant

Enantioselective [2,3]-Wittig rearrangem
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The -Wittig rearrangement of (E)-crotyl propargylic ethers, when induced with a t-BuLi /chiral bis(oxazoline) complex, is shown to provide high enantioselectivity (up to 89% ee) along with high diastereoselectivity.