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ChemInform Abstract: Highly Enantioselective Chiral Base Mediated [2,3]-Wittig Rearrangement.

โœ Scribed by S. E. GIBSON; P. HAM; G. R. JEFFERSON


Publisher
John Wiley and Sons
Year
2010
Weight
31 KB
Volume
29
Category
Article
ISSN
0931-7597

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The external chiral ligand-induced enantioselective [2,3]-Wittig rearrangements of crotyl benzyl ethers and crotyl propargylic ethers are described. The most notable is that treatment of (E)-crotyl propargylic ethers with a t-butyllithium/(S;S)-bis(oxazoline) complex provides a relatively high enant

ChemInform Abstract: Enantioselective [2
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Enantioselective [2,3]-Wittig Rearrangement Induced by Asymmetric Lithiation with a t-Butyllithium / Chiral Bis(oxazoline) System. -The use of a chiral bis(oxazoline) is effective as ligand for the enantioselective [2,3]-Wittig rearrangement of (E)-and (Z)-propargyl ethers. -(TOMOOKA,