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Enantioposition-selective alkynylation of biaryl ditriflates by palladium-catalyzed asymmetric cross-coupling

โœ Scribed by Takashi Kamikawa; Yasuhiro Uozumi; Tamio Hayashi


Book ID
103403461
Publisher
Elsevier Science
Year
1996
Tongue
French
Weight
228 KB
Volume
37
Category
Article
ISSN
0040-4039

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Enantioposition-selective arylation of b
โœ Takashi Kamikawa; Tamio Hayashi ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 869 KB

Asymmetric cross-coupling of achiral biaryl ditriflates with aryl Grignard reagents in the presence of 1 equiv of lithium bromide and 5 tool % of palladium complex PdC12[(S)-alaphos], where alaphos stands for (2dimethylamino)propyldiphenylphosphine, gave axially chiral monophenylation products with