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Enantiomeric separation of fluorescent, 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate, tagged amino acids

✍ Scribed by Maria Pawlowska; Shushi Chen; Daniel W. Armstrong


Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
714 KB
Volume
641
Category
Article
ISSN
1873-3778

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Synthesis of a Fluorescent Derivatizing
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A highly reactive amine derivatizing reagent, 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate, has been synthesized. In a rapid, one-step procedure, the compound reacts with amino acids to form stable unsymmetric urea derivatives which are readily amenable to analysis by reversed phase HPLC. Studies