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Increasing the Sensitivity of 6-Aminoquinolyl-N-hydroxysuccinimidyl Carbamate Amino Acid Analysis: A Simple Solution

✍ Scribed by Dan L. Crimmins; Ragimol Cherian


Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
113 KB
Volume
244
Category
Article
ISSN
0003-2697

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A highly reactive amine derivatizing reagent, 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate, has been synthesized. In a rapid, one-step procedure, the compound reacts with amino acids to form stable unsymmetric urea derivatives which are readily amenable to analysis by reversed phase HPLC. Studies