𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Enantiomeric resolution of DNS-amino acids by ligand exchange chromatography: Comparison of different chiral amino acid amides as additives to the mobile phase

✍ Scribed by A. M. Girelli; M. Sinibaldi

Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
315 KB
Volume
2
Category
Article
ISSN
0899-0042

No coin nor oath required. For personal study only.

✦ Synopsis

A study developing enantiomeric separations by metal chelate additives to the mobile phase in reversed-phase liquid chromatography is reported. In particular the use of Cu(I1) complexes of L-prolinamide (L-ProNH,) and Lvalinamide (L-ValNH,) is examined and discussed. Interestingly, for a series of DNS-amino acids these selectors show higher enantioselectivity than that obtained with the corresponding nonderivatized amino acid-Cu(I1) complexes.

πŸ“œ SIMILAR VOLUMES

Enantiomeric resolution of dansyl amino
Enantiomeric resolution of dansyl amino acids by microcolumn liquid chromatography with Ξ³-cyclodextrin as a mobile phase additive
✍ Toyohide Takeuchi πŸ“‚ Article πŸ“… 1992 πŸ› John Wiley and Sons 🌐 English βš– 415 KB πŸ‘ 1 views

## Abstract Enantiomeric resolution of dansyl amino acids by microcolumn liquid chromatography with γ‐cyclodextrin as a mobile phase additive has been investigated. The separation factor for the enantiomers increased with increasing γ‐cyclodextrin concentration as well as with decreasing acetonitri