## Abstract Dansyl derivatives of racemic phenylalanine and its analogs have been resolved by microcolumn liquid chromatography with γ‐cyclodextrin as mobile phase additive. The enantioselectivity of the system was influenced by the concentrations of both γ‐cyclodextrin and acetonitrile in the mobi
Enantiomeric resolution of dansyl amino acids by microcolumn liquid chromatography with γ-cyclodextrin as a mobile phase additive
✍ Scribed by Toyohide Takeuchi
- Publisher
- John Wiley and Sons
- Year
- 1992
- Tongue
- English
- Weight
- 415 KB
- Volume
- 4
- Category
- Article
- ISSN
- 1040-7685
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
Enantiomeric resolution of dansyl amino acids by microcolumn liquid chromatography with γ‐cyclodextrin as a mobile phase additive has been investigated. The separation factor for the enantiomers increased with increasing γ‐cyclodextrin concentration as well as with decreasing acetonitrile concentration in the mobile phase. The present method was successful for the resolution of twelve dansyl amino acid enantiomeric pairs.
📜 SIMILAR VOLUMES
## Abstract The effects of γ‐cyclodextrin and bovine serum albumin as mobile phase additives on fluorescence intensity and retention of dansyl amino acids (Dns‐AAs) have been examined in microcolumn liquid chromatography. Polymercoated mixed‐functional silica packings were employed for the separati
A study developing enantiomeric separations by metal chelate additives to the mobile phase in reversed-phase liquid chromatography is reported. In particular the use of Cu(I1) complexes of L-prolinamide (L-ProNH,) and Lvalinamide (L-ValNH,) is examined and discussed. Interestingly, for a series of D
Enantiomeric separation of 21 amino acids derivatized with fluoresceine isothiocyanate isomer I (FITC) has been studied by micellar electrokinetic chromatography using beta- and gamma-cyclodextrin (CD) as chiral selectors. Chiral resolution of 21 FITC derivatives of amino acids was achieved with bot