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Enantiomeric resolution of dansyl amino acids by microcolumn liquid chromatography with γ-cyclodextrin as a mobile phase additive

✍ Scribed by Toyohide Takeuchi


Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
415 KB
Volume
4
Category
Article
ISSN
1040-7685

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✦ Synopsis


Abstract

Enantiomeric resolution of dansyl amino acids by microcolumn liquid chromatography with γ‐cyclodextrin as a mobile phase additive has been investigated. The separation factor for the enantiomers increased with increasing γ‐cyclodextrin concentration as well as with decreasing acetonitrile concentration in the mobile phase. The present method was successful for the resolution of twelve dansyl amino acid enantiomeric pairs.


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